|
Symbol Name ID |
Sod2
superoxide dismutase 2, mitochondrial MGI:98352 |
| Darker colors indicate more annotations |
| Human Phenotypes | Cerebral hemorrhage |
Abnormal cerebral vascular morphology |
Stroke |
Anorexia |
Dysphagia |
Spasticity |
Cerebral calcification |
Calcification of falx cerebri |
Abnormality of the nervous system |
Aplasia/Hypoplasia of the cerebellum |
Spinal cord compression |
Ataxia |
Clumsiness |
Abnormality of extrapyramidal motor function |
Chorea |
Myoclonus |
Tremor |
Postural tremor |
Abnormal pyramidal sign |
Hemiplegia/hemiparesis |
Depression |
Psychosis |
Atypical behavior |
Polydipsia |
Polyphagia |
Cognitive impairment |
Mental deterioration |
Dementia |
Motor deterioration |
Central sleep apnea |
Reduced tendon reflexes |
Hyporeflexia |
Dystonia |
Postural instability |
Polyneuropathy |
Seizure |
Paresthesia |
| Disease(s) Associated with SOD2 | |||||||||||||||||||||||||||||||||||||
| inclusion body myositis | |||||||||||||||||||||||||||||||||||||
| Leber hereditary optic neuropathy | |||||||||||||||||||||||||||||||||||||
| multiple myeloma | |||||||||||||||||||||||||||||||||||||
| neuronal ceroid lipofuscinosis | |||||||||||||||||||||||||||||||||||||
| pancreatic cancer | |||||||||||||||||||||||||||||||||||||
| pseudoxanthoma elasticum | |||||||||||||||||||||||||||||||||||||
| systemic lupus erythematosus | |||||||||||||||||||||||||||||||||||||
| type 1 diabetes mellitus |
| Mouse Phenotypes | seizures |
abnormal brain morphology |
abnormal brainstem morphology |
abnormal trigeminal V mesencephalic nucleus morphology |
abnormal trigeminal motor nucleus morphology |
abnormal forebrain morphology |
abnormal thalamus morphology |
abnormal hippocampus morphology |
abnormal cerebral cortex morphology |
abnormal frontal lobe morphology |
abnormal cerebellum morphology |
brain vacuoles |
short photoreceptor inner segment |
short photoreceptor outer segment |
abnormal retina rod cell outer segment morphology |
retina photoreceptor degeneration |
neuron degeneration |
abnormal optic nerve morphology |
neurodegeneration |
axon degeneration |
spongiform encephalopathy |
|
| Availability | Mouse Genotype | |||||||||||||||||||||
| Sod2tm1Cje/Sod2tm1Cje | ||||||||||||||||||||||
| Sod2tm1Leb/Sod2tm1Leb | ||||||||||||||||||||||
| Sod2tm1Kskk/Sod2tm1Kskk Tg(BEST1-rtTA,tetO-cre)1Yzl/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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